Stable solution for dental remineralization

Details Stable solution for dental remineralization Stable solution for dental remineralization

1978-10-13

1980-01-15

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Fluorine or fluorine compound containing

424 49, 424 54, 424 57, A61K 716, A61K 718, A61K 722

Patent

active

041839153

ABSTRACT:
An aqueous solution useful for remineralizing subsurface carious lesions of dental enamel which solution contains sources of calcium ions and phosphate ions as well as fluoride ions and further includes as an agent to stabilize the solution against precipitation, an antinucleating agent such as ethylenediamine tetramethylenephosphonic acid or water soluble salt thereof, the pH of the solution being about 5-9, preferably close to physiological conditions, such as about 6.8-7.5.

REFERENCES:
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patent: 3298956 (1967-01-01), Irani et al.
patent: 3336221 (1967-08-01), Ralston
patent: 3434969 (1969-03-01), Ralston
patent: 3625569 (1972-02-01), Medcalf
patent: 3671644 (1972-06-01), Irani et al.
patent: 3792152 (1974-02-01), Kim
patent: 3832396 (1974-08-01), Irani et al.
patent: 4097588 (1978-06-01), Levine
patent: 4110429 (1978-08-01), Gaffar et al.
Meyer and Nancollas Calc. Tiss. Res. 13:295-303 (1973), The Influence of Multi-Dentate Organo-Phosphonates on the Crystal Growth of Hydroxy Apatite.
Briner et al., Calc. Tiss. Res. 7:249-256 (1971), Factors Affecting the Rate of Post-Eruptive Maturation of Dental Enamel.
Monsanto Co. Brochure "Dequest" Organophosphorus Compounds, Feb. 1971.

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