Polymeric competitive protein binding adsorbents for radioassey

Details Polymeric competitive protein binding adsorbents for radioassey Polymeric competitive protein binding adsorbents for radioassey

1973-11-05

1976-09-14

Sebastian, Leland A.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

260112R, 424359, A61K 4300, A61K 3900, A61K 3706

Patent

active

039807649

ABSTRACT:
Serum protein comprising specific binding proteins such as antibodies, B.sub.12 intrinsic factor, thyroxin binding globulin and the like may be copolymerized with globulin constituents of serum by the action of ethylchloroformate to form readily packed insoluble precipitates which, following purification as by washing, are eminently suited for employment as competitive binding protein absorbents in radioassay procedures.

REFERENCES:
patent: 2957808 (1960-10-01), Campbell
patent: 3410839 (1968-11-01), De Carvalho
avrameas et al., "Biologically Active Water-Insoluble Protein Polymers," in The Journal of Biological Chemistry, vol. 242, No. 7, Apr. 10, 1967, pp. 1651-1659.

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