6-N-Heterocyclyl-3-tetrazolyl-penicillins

Details 6-N-Heterocyclyl-3-tetrazolyl-penicillins 6-N-Heterocyclyl-3-tetrazolyl-penicillins

1979-08-01

1981-08-11

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424267, 424263, 424273R, 424273B, 424270, 424251, 546112, 546138, 546270, 546272, 2602452R, C07D40202

Patent

active

042834023

ABSTRACT:
This invention relates to a new class of penicillins (I) and their pharmaceutically acceptable salts which are useful as antibiotics: ##STR1## wherein the stylized radical (hereafter referred to as R'): ##STR2## attached to the 6-amino nitrogen moiety of the penicillin nucleus represents a mono- or polycyclic N-containing heterocyclic group; and R is, inter alia, hydrogen, substituted and unsubstituted: alkyl, aryl, alkenyl, heterocyclylalkyl, heterocyclylalkenyl, aralkenyl, aralkyl, --NR.sub.2, COOR, CONR.sub.2,--OR, or CN.

REFERENCES:
patent: 4081455 (1978-03-01), Kuhla
patent: 4143039 (1979-03-01), Barth

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