Thio-.beta.-lactam cephalosporins

Details Thio-.beta.-lactam cephalosporins Thio-.beta.-lactam cephalosporins

1976-02-20

1977-04-19

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424246, C07D50120

Patent

active

040187608

ABSTRACT:
Thio-.beta.-lactam cephalosporins of the general formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, trihaloethyl, alkali metal or alkaline earth metal; R.sub.1 is hydrogen, lower alkyl, cycloalkyl, phenyl, phenoxy, phenyl-lower alkyl or certain heterocyclic groups; R.sub.2 is hydrogen, amino, carboxy, hydroxy or ureido; and X is hydrogen, hydroxy, lower alkylthio, lower alkylthiadiazolyl, lower alkyltetrazolyl or lower alkanoyloxy, are useful as antimicrobial agents.

REFERENCES:
patent: 3971780 (1975-02-01), Cimarusti

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