Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546123, A61K 31435, C07D47104

Patent

active

046491449

ABSTRACT:
The present invention relates to a 1,8-naphthyridine derivative of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are the same or different and each hydrogen or lower alkyl having 1 to 5 carbon atoms; and esters thereof and salts thereof and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful antibacterial agents.

REFERENCES:
patent: 4248629 (1981-08-01), Grohe et al.
patent: 4341784 (1982-07-01), Matsumoto et al.
patent: 4359578 (1982-11-01), Matsumoto et al.
patent: 4382937 (1983-05-01), Matsumoto et al.
"Organic Chemistry", Morrison & Boyd, 2nd Ed., Chapter 27, 1960.

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