N-acyl acidic amino acid diamide derivative, a salt thereof, and

Details N-acyl acidic amino acid diamide derivative, a salt thereof, and N-acyl acidic amino acid diamide derivative, a salt thereof, and

1984-12-03

1986-09-09

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

549 68, 549 76, 514234, 549 77, 549283, 514255, 549288, 549404, 514316, 549407, 549463, 514320, 549467, 514326, 549494, 514422, 549496, 514457, 514443, 514444, 514459, 514469, 514471, 514472, 544 85, 544 86, 544130, 544141, 544145, 544146, 544147, 546187, 546208, 546196, 546202, 546207, 546212, 546214, 548517, 548524, 548527, 549 57, 549 58, A61K 3134, A61K 3116, C07D30754, C07C103147

Patent

active

046109838

ABSTRACT:
This invention relates to a novel N-acyl acidic amino acid diamide derivative represented by the general formula or a salt thereof: ##STR1## wherein each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4, which may be the same or different, represents a hydrogen atom or a substituted or unsubstituted alkyl, cycloalkyl, alkenyl or aralkyl group, or R.sup.1 and R.sup.2 and/or R.sup.3 and R.sup.4, when taken together with the respective adjacent nitrogen atoms, form a substituted or unsubstituted heterocyclic group; R.sup.5 represents a substituted or unsubstituted cycloalkyl, acyl or heterocyclic group; A represents a bond or a substituted or unsubstituted alkylene, alkenylene or alkadienylene group; and n is 1, 2 or 3. Said compound has an anti-ulcer activity which is effective to human beings and animals. This disclosure relates to such a compound, to a process for the production thereof and to an anti-ulcer agent containing the same.

REFERENCES:
patent: 4143070 (1979-03-01), Walker
patent: 4517378 (1985-05-01), Vasta

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