Piperidine opioid antagonists

Details Piperidine opioid antagonists Piperidine opioid antagonists

1990-10-30

1991-11-12

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3144

Patent

active

050648349

ABSTRACT:
This invention provides trans-3,4 1-substituted-3-substituted-4-methyl-4-(3-substituted phenyl)piperidines as opioid antagonists capable of blocking the mu or kappa receptors in the brain.

REFERENCES:
patent: 3936468 (1976-10-01), Yamamoto et al.

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