Triazolo[1,5-c]pyrimidines substituted by nitrogen-containing he

Details Triazolo[1,5-c]pyrimidines substituted by nitrogen-containing he Triazolo[1,5-c]pyrimidines substituted by nitrogen-containing he

1983-03-03

1986-02-25

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514227, 514258, 544227, 544258, 544 582, 544 60, 544 61, 544 81, 544 82, 544118, 544122, 544263, 544295, A61K 31505, A61K 31535, A61K 3154, C07D47104

Patent

active

045729107

ABSTRACT:
1,2,4-Triazolo[1,5-c]pyrimidines substituted at the 5 or 7 positions through a nitrogen atom which is part of a heterocyclic ring have been found to have potent bronchodilator activity. Methods for inducing bronchodilation, pharmaceutical compositions and synthetic processes are also disclosed.

REFERENCES:
patent: 4269980 (1981-05-01), Hardy et al.
G. W. Miller et al.; J. Chem. Soc., 1963, 5642 and 3357.
W. Broadbent et al., J. Chem. Soc., 1963, 3369.
Temple et al., J. Org. Chem., 1963, 33, 530.
D. J. Brown et al., Aust. J. Chem., 1978, 31, 2505.
D. J. Brown et al., Aust. J. Chem., 1979, 32, 1585.
D. J. Brown et al., Aust. J. Chem., 1980, 33, 1147.

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