Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1990-04-10
1991-08-20
Reamer, James H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
560172, 560169, 560 38, C07C22718
Patent
active
050416430
ABSTRACT:
A process for the production of R(+)-aminocarnitine and S(-)-aminocarnitine is disclosed by resolution of the mixture of the diastereoisomers of N-(alpha-methylbenzyl) aminocarnitine benzyl ester chloride, wherein the separated diastereoisomers are subsequently debenzylated to give R(+)-aminocarnitine chloride and S(-)-aminocarnitine chloride.
REFERENCES:
patent: 4521432 (1985-06-01), Kanamaru et al.
patent: 4767781 (1988-08-01), Shinagawa et al.
patent: 4781863 (1988-11-01), Griffith
Misiti Domenico
Tinti Maria O.
Reamer James H.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
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