Process for the production of R(+)-aminocarnitine and S(-)-amino

Details Process for the production of R(+)-aminocarnitine and S(-)-amino Process for the production of R(+)-aminocarnitine and S(-)-amino

1990-04-10

1991-08-20

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

560172, 560169, 560 38, C07C22718

Patent

active

050416430

ABSTRACT:
A process for the production of R(+)-aminocarnitine and S(-)-aminocarnitine is disclosed by resolution of the mixture of the diastereoisomers of N-(alpha-methylbenzyl) aminocarnitine benzyl ester chloride, wherein the separated diastereoisomers are subsequently debenzylated to give R(+)-aminocarnitine chloride and S(-)-aminocarnitine chloride.

REFERENCES:
patent: 4521432 (1985-06-01), Kanamaru et al.
patent: 4767781 (1988-08-01), Shinagawa et al.
patent: 4781863 (1988-11-01), Griffith

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