Enhancing the cutaneous penetration of pharmacologically active

Details Enhancing the cutaneous penetration of pharmacologically active Enhancing the cutaneous penetration of pharmacologically active

1990-09-20

1991-09-03

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424 45, 514946, A61K 600

Patent

active

050453173

ABSTRACT:
Method and compositions for enhancing the cutaneous penetration of topically or transdermally delivered pharmacologically active agent. The compositions include various urethane compounds as permeation enhancers, the urethane compounds formed from reaction of a monomeric organic diisocyanate with a hydroxy- or hydroxy/alkoxy-terminated linear alkylene or polyalkylene glycol or polyether.

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