Method and means for allergy diagnosis

Details Method and means for allergy diagnosis Method and means for allergy diagnosis

1988-10-17

1991-08-20

Nucker, Christine

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

436541, 436804, 435 29, G01N 33552

Patent

active

050413902

ABSTRACT:
The histamine in a sample is determined by contacting the sample with a histamine binding agent, such as glass, which has been treated, e.g., with a polar organic polymer, to reduce the affinity of the agent for an interfering component of the sample while substantially retaining the agent's histamine binding capacity. Such an agent facilitates determination of histamine in whole blood samples. Preferably, the agent is provided as a conglomerate of histamine-binding bodies, such as glass fibers, in a binder. Preferred binders are polyvinyl acetate, a vinyl acetate/ethylene copolymer, and polyvinyl alcohol or combinations thereof.

REFERENCES:
patent: 4550085 (1985-10-01), Skov et al.
Merck Index 10th Edition, p. 1395, 1983.

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