Process for the production of 2-(methylthio)-disodium barbiturat

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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C07D23902

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active

052506894

ABSTRACT:
A process for the production or 2-(methylthio)-disodium barbiturate. Thiourea, malonic acid dimethyl ester and sodium methanolate are reacted to disodium thiobarbiturate. The disodium thiobarbiturate then is reacted with methyl bromide, optionally in the presence of a base, to the end product.

REFERENCES:
patent: 4692524 (1987-09-01), Hassig

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