Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1992-05-11
1993-10-05
Griffin, Ronald W.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435119, 536 41, C12P 1902
Patent
active
052504220
ABSTRACT:
Incubation of 13.beta.-hydroxy ivermectin aglycone with a species of Bacillus subtilis or the incubation of 13-deoxy ivermectin aglycone with a mixed culture of a species of Bacillus subtilis and of Streptomyces griseus results in the production of 13-.beta. ivermectin monoglucopyranoside as the major product and of 5-.beta. ivermectin monoglucopyranoside as the minor product.
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Arison Byron H.
Chen Shieh-Shung T.
Inamine Edward S.
Petuch Brian R.
White Raymond F.
Ayler Sylvia A.
DiPrima Joseph F.
Griffin Ronald W.
Merck & Co. , Inc.
Rose David L.
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