Apparatus and method for determining tissue characteristics

Details Apparatus and method for determining tissue characteristics Apparatus and method for determining tissue characteristics

1997-12-12

2000-04-25

Lateef, Marvin M.

Surgery

Diagnostic testing

Detecting nuclear, electromagnetic, or ultrasonic radiation

2503413, 2504612, 356369, A61B 600

Patent

active

060554517

ABSTRACT:
An apparatus and method embodying the invention include utilizing a device intended to be inserted into a patient's body to determine a characteristic of a target tissue. In one apparatus and method, a device illuminates the target tissue with amplitude modulated excitation electromagnetic radiation, and the device senses a returned electromagnetic radiation. A phase shift between the excitation and return electromagnetic radiation is determined, and the phase shift is used to determine characteristics of the target tissue. A demodulation factor, representing ratios of the AC and DC components of the excitation and return electromagnetic radiation may also be calculated and used to determine characteristics of the target tissue. In another apparatus and method embodying the invention, a device illuminates a target tissue with polarized electromagnetic radiation, and a return electromagnetic radiation is sensed. The amplitude of the returned electromagnetic radiation is sensed in mutually perpendicular planes, and this information is used to determine an anisotropy factor. The anisotropy factor, in turn, is used to determine characteristics of the target tissue. In either of the above-described methods, the return radiation could be a portion of the excitation radiation that has been reflected or scattered from the target tissue, or the returned electromagnetic radiation could be fluorescent emissions generated by endogenous or exogenous fluorophores located in the target tissue.

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