Zymomonas with improved ethanol production in medium...

Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...

Reexamination Certificate

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C435S252300, C435S440000

Reexamination Certificate

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07897396

ABSTRACT:
Through screening of aZymomonasmutant library the himA gene was found to be involved in the inhibitory effect of acetate onZymomonasperformance. Xylose-utilizingZymomonasstrains further engineered to reduce activity of the himA gene were found to have increased ethanol production in comparison to a parental strain, when cultured in mixed-sugars medium comprising xylose, and, in particular, in the presence of acetate.

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