Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-09-12
1997-04-08
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4351721, 4351723, 536 237, 536 241, C07H 2104, C12P 2100, C12N 1563
Patent
active
056186924
ABSTRACT:
A new gene from Bacillus cereus has been characterized which codes for a protein conferring resistance to the antibiotic zwittermicin A produced by some strains of the bacteria. The resistance gene, designated zmaR, is found to be present in almost all strains of the bacteria which are known to natively have the ability to synthesize zwittermicin A, and thus allows tests for the presence of the gene to serve as a test to be used with new strains to assay for zwittermicin A production. The gene also has use in increasing production of the antibiotic by producing strains.
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Handelsman Jo
Milner Jocelyn L.
Stabb Eric
Stewart Sandra J.
Stohl Elizabeth A.
Tran Paul B.
Wisconsin Alumni Research Foundation
Zitomer Stephanie W.
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