Zwitterionic polymers

Details Zwitterionic polymers Zwitterionic polymers

2007-11-27

2007-11-27

Pezzuto, Helen L (Department: 1713)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Polymers from only ethylenic monomers or processes of...

C526S091000, C526S145000, C526S146000, C526S147000, C526S161000, C526S172000, C526S193000, C526S204000, C526S213000, C526S220000, C526S222000, C526S262000, C526S287000, C526S303100, C526S310000, C526S319000, C524S710000

Reexamination Certificate

active

11025968

ABSTRACT:
Polymers may be made from zwitterionic monomers having controlled architectures and molecular weights, using living polymerisations such as group or atom transfer radical polymerisation. For instance polymers may be formed by atom transfer radical polymerisation using a copper chloride catalyst, a ligand which is water soluble, and a water soluble tertiary alkyl halide initiator to form homopolymers having controlled polydispersities of less than 1.5 and block copolymers with other hydrophilic or hydrophobic monomers. One suitable zwitterionic monomer is 2-methacryloyloxy-2′-trimethylammoniumethyl phosphate inner salt. The block copolymers may spontaneously form micelles, believed to have zwitterionic, for instance phosphorylcholine, groups at the external surface, which may be useful as drug delivery systems with improved biocompatibility.

REFERENCES:
patent: 5789487 (1998-08-01), Matyjaszewski et al.
patent: 5807937 (1998-09-01), Matyjaszewski et al.
patent: WO 93/01221 (1993-01-01), None
patent: WO 94/16749 (1994-08-01), None
patent: WO 95/20407 (1995-08-01), None
patent: WO 96/30421 (1996-10-01), None
patent: WO 98/07758 (1998-02-01), None
patent: WO 98/22516 (1998-05-01), None
patent: WO 98/30615 (1998-07-01), None
patent: WO 98/40415 (1998-09-01), None
patent: WO 01/09208 (2001-02-01), None
Yung et al. Biomaterials, 19 (1998), 31-40.
Oishi et al. Polymer Journal, 32(4), 378-380 (2000).
Wang et al., “Facile synthesis of well-defined water-soluble polymersviaatom transfer radical polymerization in aqueous media at ambient temperature,”Chem. Commun., (1999), pp. 1817-1818.
Wang et al., “Scope and Limitations of Atom Transfer Radical Polymerisation in Aqueous Media,”Polymer Preprints 2000, vol. 41, No. 1, pp. 413-414.
Feng et al., Journal of Polymer Science, Part A: Polymer Chemistry (2004), 42(12), 2931-2942.
Miyamoto et al, Journal of Applied Polymer Science (2004), 91(2), 827-832.
Oishi et al., Polymer Journal (Tokyo) (1998), 30(1), 17-22.

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