Zwitterionic polymer blend materials

Details Zwitterionic polymer blend materials Zwitterionic polymer blend materials

2005-08-02

2005-08-02

Nutter, Nathan M. (Department: 1711)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

C525S209000, C525S210000, C525S211000, C525S222000, C525S223000

Reexamination Certificate

active

06924338

ABSTRACT:
A polymer blend for use in a biomedical application comprising: (A) a polymer A, bearing zwitterionic pendant groups; and (B) a hydrophobic addition polymer B, selected from the group consisting silyl(alk)acrylates, alkyl(alk)acrylamides, dialkyl(alk)acrylamides, and alkyl(alk)acrylate polymers, wherein the structure of the blend exhibits phase separation forming a micro-phase segregated structure at a surface. Articles, methods of production and liquid blend compositions are also disclosed. Preferably A is a copolymer of 15 to 30 mole % 2-methacryloyloxyethy1-2-trimethylammonium ethyl phosphate inner salt and 85 to 70 mole % of a C6-18alkyl methacrylate, and B is a homopolymer of a C4-18alkyl(meth)acrylate, blended in weight proportions of 1:1 to 1:50.

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Hayward et al., “Biomembrane surfaces as models for polymer design: the potential for haemocompatibility,”Biomaterials, (May 1984), vol. 5, pp. 135-142.

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