Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine conta

Details Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine conta Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine conta

1985-07-29

1987-08-04

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544117, 544212, 544238, 544295, 544333, 544350, 544362, 540520, 546122, 546134, 546136, 546137, 546155, A61K 3144, C07D47104

Patent

active

046847278

ABSTRACT:
Zwitterionic bicyclic compounds are disclosed which are useful as anti-allergic, anti-inflammatory and/or cytoprotective agents. Pharmaceutical compositions and methods of treatment employing such compounds are also disclosed.

REFERENCES:
Kappe et al., Monatshefte fur Chemie, 99, pp. 2157-2166 (1968).
Merchant et al., Curr. Sci., 49(1), pp. 20-21, (1980); Chem. Abst. vol. 92-181059u (1980).
Wittmann et al., Z. Naturforsch., B: Anorg. Chem., Org. Chem., 33B(12), pp. 1540-1546 (1978); Chem. Abst. vol. 90-121339 (1979).
Bowman et al., "The Synthesis of Some Dialkylamino-2-quinolones," Journal of the Chemical Society, pp. 1350-1353 (1964).

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