Zinc salt of all-trans-retinoic acid for the treatment of acne

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Bacterium or component thereof or substance produced by said...

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2604299, 424344, A61K 31315, C07F 306

Patent

active

042140005

ABSTRACT:
A zinc salt of retinoic acid has been prepared and found to have significant anti-acne activity, similar to that of retinoic acid, but with less of a tendency to cause flaking or irritation at anti-acne effective concentrations.

REFERENCES:
patent: 3729568 (1973-04-01), Kligman
patent: 3856941 (1974-12-01), Turner
patent: 3906108 (1975-09-01), Felty
patent: 3949072 (1976-04-01), Tenta
patent: 4039681 (1977-08-01), Abdel-Monem
patent: 4053630 (1977-10-01), Yu et al.
Chemical Abstracts 76:158354x (1972).

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