Zinc ring protein

Details Zinc ring protein Zinc ring protein

1998-08-03

1999-12-07

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530350, 530358, A61K 3800, A61K 3816, C07K 100

Patent

active

059983728

ABSTRACT:
The invention provides a human zinc RING protein (ZIRI) and polynucleotides which identify and encode ZIRI. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ZIRI.

REFERENCES:
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Barlow, P.N. et al., "Structure of the C.sub.3 HC.sub.4 Domain by .sup.1 H-nuclear Magnetic Resonance Spectroscopy. A New Structual Class of Zinc-finger", J. Mol. Biol., 237: 201-211 (1994).
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Lomax, M. et al, "The gene for a RING zinc finger protein is expressed in the inner ear," EMBL Database, Accession No. AF037204, Heidelberg, Germany, Jan. 9, 1998.
Tranque et al., Proc. Natl. acad. Sci. USA, 93, 3105-3109, Apr. 1996.

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