Chemistry: analytical and immunological testing – Metal or metal containing – Present in biological fluids
Patent
1986-10-22
1988-02-16
Richman, Barry S.
Chemistry: analytical and immunological testing
Metal or metal containing
Present in biological fluids
2504591, 356 36, 436 81, 436 96, 436 98, 436172, 436174, 436176, 436910, G01N 128, G01N 2164, G01N 3348
Patent
active
047255552
ABSTRACT:
A system for determining zinc protoporphyrin levels in whole blood using hematofluorometry without the need for oxygenation of the hemoglobin by derivatizing the hemoglobin to form a new compound having essentially the same spectral properties as oxygenated hemoglobin. A preferred reagent includes cyanide as the active ingredient.
REFERENCES:
patent: 3663175 (1972-05-01), Depositar et al.
patent: 3874852 (1975-04-01), Hamill
patent: 3973129 (1976-08-01), Blumberg et al.
patent: 4055768 (1977-10-01), Bromberg
patent: 4178917 (1979-12-01), Shapiro
Blumberg et al, Clin. Chem., vol. 23, No. 2, pp. 270-274, 1977.
Labbe Robert F.
Rettmer Rebecca L.
Helena Laboratories Corporation
Hill Jr. Robert J.
Richman Barry S.
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