Zinc-protamine-alpha interferon complex

Details Zinc-protamine-alpha interferon complex Zinc-protamine-alpha interferon complex

1987-02-24

1989-08-01

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

424 854, A61K 4502

Patent

active

048532185

ABSTRACT:
An insoluble zinc-protamine alpha interferon complex useful as an injectable sustained release dosage form for administering alpha interferon is disclosed.

REFERENCES:
patent: 3912807 (1975-10-01), Alhern et al.
patent: 4289690 (1981-09-01), Pestka et al.
patent: 4496537 (1985-01-01), Kwan
patent: 4605555 (1984-09-01), Sato et al.
CA, vol. 103, No. 13, Sep. 30, 1985, Abst. 99718v.
Nagata et al., Nature, vol. 284, pp. 316-320.
Rubenstein, Biochimica et Biophysica Acta, 696 (1982) pp. 5-16.
U.S. Pharmacopeia, 16th ed., (1985), pp. 540-541, 2007.

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