Zinc-monocysteine complex and method of using zinc-cysteine...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing

Reexamination Certificate

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C514S494000

Reexamination Certificate

active

10610368

ABSTRACT:
A method of providing zinc to a subject in need of treatment includes administering to the subject an effective amount of a zinc-cysteine complex. The zinc-cysteine complex is preferably a zinc-monocysteine complex. The complexes of zinc-cysteine of the present invention increase the activity of antioxidant enzymes catalase and glutathione peroxidase, and the antioxidant protein metallothionein. The complexes of zinc-cysteine of the present invention protect retinal pigment epithelial cells from increasing hydrogen peroxide concentrations.

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Hideyo Shindo and Theodore L. Brown, Infrared Spevctra of Complexes of L-Cysteine and Related Compounds with Zinc(II), Cadmium(II), Mercury(II), and Lead(II), Journal of the American Chemical Society, 87:9, May 5, 1965, pp. 1904-1909.

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