Zinc(II) complexes and methods related thereto

Details Zinc(II) complexes and methods related thereto Zinc(II) complexes and methods related thereto

1995-06-29

1997-06-10

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424433, 424435, 424443, 424489, 424641, 424436, 514332, 556134, 556135, A61F 902, A61K 970, A61K 3332, A61K 3144

Patent

active

056373112

ABSTRACT:
Zinc(II) complexes and methods relating thereto are disclosed. The zinc(II) complexes comprise a zinc(II) ion complexed by a multi-dentate ligand. Methods of this invention include the use of the zinc(II) complexes as anti-viral agents and/or as anti-inflammatory agents. Methods of this invention also include inhibition of viral infection, as well as inhibiting transmission of sexually transmitted diseases. Exemplary zinc(II) complexes include zinc(II):neocuproine (2:1) and zinc(II):bathocuproine disulfonic acid (2:1).

REFERENCES:
patent: 3980654 (1976-09-01), Gysling
patent: 5075469 (1991-12-01), Chevion
Duran et al., "Electrochemical Synthesis of Pyridine-2-Thionato Complexes of Zinc(II) and Cadmium(II): The Crystal Structure of 1,10-Phenanthroline-Bis(Pyridine-2-Thionato)-Zinc(II)," Polyhedron 10(2): 197-202, 1991.
Hu and Liu, "Structure of cis-Diaquabis(1,10-phenanthroline)zinc Sulfate Hexahydrate," Acta Cryst. C47:2324-2326, 1991.
Jordan et al., "Structural Dependence of the Luminescence from Bis(substituted benzenethiolato) (2,9-dimethyl-1,10-phenanthroline)zinc(II) Complexes," Inorg. Chem. 30:4588-4593, 1991.
Bell et al., "Complexes of Zinc Dialkyldithiocarbamates. Part I. Complexes with Bidentate Nitrogen Ligands; Crystal Structure of 1,10-Phenanthroline Zinc Dibutyldithiocarbamate," Inorganica Chimica Acta 156: 205-211, 1989.
Bencini et al., "Tetracyanoquinodimethane Salts of Transition-Metal Complexes. Crystal and Molecular Structures and Magnetic Properties of Tris(1,10-phenanthroline)zinc(II) Bis(tetracyanoquinodimethanide) and Tris(1,10-phenanthroline)copper(II) Bis(tetracyanoquinodimethanide)," Inorg. Chem. 28:1963-1969, 1989.
Mabrouk et al., "The Direct Electrochemical Synthesis of Zinc and Cadmium Catecholates and Related Compounds," Inorganica Chimica Acta 129:75-80, 1987.
Fitzgerald and Hathaway, "The Crystal Structure and Electronic Properties of the Complexes Acetatobis(1,10-phenanthroline)copper(II) Perchlorate Dihydrate, Acetatobis(1,10-phenanthroline)copper(II) Nitrate Dihydrate, and Acetatobis(1,10-phenanthroline) zinc(II) Tetrafluoroborate Dihydrate," J. Chem. Soc. Dalton Trans. 141-149, 1985.
Cremers et al., "Structure of (1,10-Phenanthroline)bis(4-toluenethiolato)zinc(II)," Acta Cryst. B36: 3097-3099, 1980.
Monge et al., "The Adduct Zinc Dicyanide-2,9-Dimethyl-1,10-phenanthroline," Acta Cryst. B33:2329-2331, 1977.
Reimann et al., "The Crystal and Molecular Structure of Dicholoro(1,10-phenanthroline)zinc," Inorganic Chemistry 5(7):1185-1189, 1966.

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