Zinc-free and low-zinc insulin preparations having improved...

Details Zinc-free and low-zinc insulin preparations having improved... Zinc-free and low-zinc insulin preparations having improved...

2005-11-01

2005-11-01

Tate, Christopher R. (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S560000, C514S004300, C530S303000, C530S304000

Reexamination Certificate

active

06960561

ABSTRACT:
The invention relates to a formulation comprising a polypeptide selected from at least one of insulin, an insulin metabolite, an insulin analog, and an insulin derivative; at least one surfactant; optionally at least one preservative; and optionally at least one of an isotonicizing agent, a buffer or an excipient, wherein the formulation is free from or low in zinc. The invention also relates to the production of such insulin preparations and their use as pharmaceutical formulations.

REFERENCES:
patent: 4153689 (1979-05-01), Hirai et al.
patent: 5506203 (1996-04-01), Bäckström et al.
patent: 6211144 (2001-04-01), Havelund
patent: 0 166 529 (1986-01-01), None
patent: 0 200 383 (1986-12-01), None
patent: 0 200 383 (1986-12-01), None
patent: WO 98/42749 (1998-10-01), None
patent: WO 98/42749 (1998-10-01), None
patent: WO 00/74736 (2000-12-01), None
patent: WO 00/074736 (2002-08-01), None
H. Thurow and K. Geisen, “Stabilisation of dissolved proteins against denaturation at hydrophobic interfaces,”Diabetologia, 27:212-18 (1984).
W.D. Lougheed et al., “Physical Stability of Insulin Formulations,”Diabetes, 32: 424-32 (1983).

Affiliated with

Also associated with

Rating

Zinc-free and low-zinc insulin preparations having improved... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Zinc-free and low-zinc insulin preparations having improved..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Zinc-free and low-zinc insulin preparations having improved... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3461173