Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-11-07
1983-01-11
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424253, 544226, 544267, A61K 31555, C07F 306, C07F 966
Patent
active
043681972
ABSTRACT:
There is disclosed zinc complexes of amine salts of theophylline. The preferred compound disclosed is the zinc complex of aminophylline. These compounds are useful as bronchodilators and have antibronchospasmotic activity. They are substantially insoluble and do not impart an unpleasant taste to oral formulations. In addition, they are storage stable. The compounds are prepared by reacting a water soluble simple zinc salt with the amine salt of theophylline at temperatures of from 60.degree.-90.degree. C. for about 8 to 16 hours.
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Gardner Mark J.
Shefter Eli
Smith Francis X.
Research Corporation
Schenkman Leonard
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