Zero volume cell

Chemistry: electrical and wave energy – Apparatus – Electrolytic

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204222, 204400, G01N 2746

Patent

active

049158120

ABSTRACT:
Methods and apparatuses are described for determining the presence of an analyte in a sample suspected of containing the analyte. The method comprises contacting a concentrate of a determinable element capable of being detected by means of a semiconductive electrode with the electrode in the presence of a relatively large volume of an assay medium. The determinable element is present in the concentrate in the amount related to the amount of analyte present in the sample. The volume of the medium in diffusive communication with the concentrate is then reduced and the determinable element is detected by means of the effect that the determinable element has on the semiconductive electrode.

REFERENCES:
patent: 3420765 (1969-01-01), Uhrenholdt
patent: 3503861 (1970-03-01), Volpe
patent: 3926765 (1975-12-01), Haddad
patent: 3975238 (1976-08-01), Bean et al.
patent: 4591550 (1986-05-01), Hafeman et al.

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