Zero-mode clad waveguides for performing spectroscopy with...

Optical waveguides – Optical waveguide sensor

Reexamination Certificate

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C385S014000, C385S129000, C385S130000

Reexamination Certificate

active

06917726

ABSTRACT:
The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.

REFERENCES:
patent: 5465151 (1995-11-01), Wybourne et al.
patent: 5677769 (1997-10-01), Bendett
patent: 6510263 (2003-01-01), Maisenholder et al.
patent: 6573089 (2003-06-01), Vann
patent: 2002/0180570 (2002-12-01), Facer et al.
patent: 2003/0137313 (2003-07-01), Jannsen et al.
patent: 2003/0174992 (2003-09-01), Levene et al.
Dorre, K., et al., “Highly Efficient Single Molecule Detection in Microstructures”,Journal of Biotechnology, 86(3), (Apr. 3, 2001), 225-236.
Heinze, K. G., et al., “TTwo-photon fluorescence coincidence analysis: rapid measurements of enzyme kinetics”,Biophysical Journal, 83(3), (Sep. 2002), 1671-1681.
Kang, et al., “Investigations of Potential—Dependent Fluxes of Ionic Permeates in Gold Nanotubule Membranes Prepared Via the Template Method”,Langmuir, 17(9), (2001), 2753-2759.
McDonald, J. C., et al., “Fabrication of a configurable, single-use microfluidic device”,Analytical Chemistry, 73(23), (Dec. 1, 2001), 5645-5650.
Schwille, P., et al., “Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution”,Biophysical Journal, 72(4), (Apr. 1997), 1878-1886.
Weiss, S., “Fluorescence spectroscopy of single biomolecules”,Science, 283,(5408), (Mar. 12, 1999), 1676-1683.

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