Zebrafish assay

Details Zebrafish assay Zebrafish assay

2005-06-10

2008-12-16

Bertoglio, Valarie (Department: 1632)

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

Transgenic nonhuman animal

C800S003000, C800S020000, C424S009200

Reexamination Certificate

active

07465848

ABSTRACT:
The invention includes a zebrafish assay for cardiac response.

REFERENCES:
patent: 4603209 (1986-07-01), Tsien et al.
patent: 5049673 (1991-09-01), Tsien et al.
patent: 6299858 (2001-10-01), Serbedzija et al.
patent: 6380458 (2002-04-01), Lin
patent: 6656449 (2003-12-01), Serbedzija et al.
patent: 2002/0165364 (2002-11-01), Tsien et al.
patent: 2003/0074682 (2003-04-01), Langheinrich
patent: 2003/0161787 (2003-08-01), Langheinrich
patent: 2003/0162292 (2003-08-01), Tsai et al.
patent: 2004/0133144 (2004-07-01), Macrae et al.
patent: 2005/0155087 (2005-07-01), Zon et al.
patent: WO01/92874 (2001-12-01), None
patent: WO2004/047634 (2004-06-01), None
Kuhl, M. Frontiers in Bioscience, 9:967-974, 2001.
Peterson RT. et al. ,PNAS, 97:12965-12969, 2000.
Barrionuevo & Burggren “02consumption and heart rate in developing zebrafish (Danio rerio): influence of temperature and ambient 02”American Physiological Society, vol. 276(2): R505-R513 (1999).
Camm et al. “Congenital and acquired long QT syndrome”European Heart Journal, vol. 21: 1232-1237 (2000).
Chen et al. “Mutations affecting the cardiovascular system and other internal organs in zebrafish”Development, vol. 123: 293-302 (1996).
Culp et al. “High-frequency germ-line transmission of plasmid DNA sequences injected into fertilized zebrafish eggs”Proc. Natl. Acad. Sci.,vol. 88: 7953-7957 (1991).
Huang et al. “Germ-Line transmission of a myocardium-specific GFP transgene reveals critical regulatory elements in the cardiac myosin light chain 2 promoter of zebrafish”Developmental Dynamics, vol. 228: 30-40 (2003).
Keating & Sanguinetti “Molecular and cellular mechanisms of cardiac arrhythmias”Cell, vol. 101(4): 569-580 (2001).
Rottbauer et al. “Growth and function of the embryonic heart depend upon the cardiac-specific 1-type calcium channel α1 subunit”Developmental Cell, vol. 1: 265-275 (2001).
Sehnert & Stainier “A window to the heart: can zebrafish mutants help us understand heart disease in humans?”Trends in Genetics, vol. 18(10): 491-494 (2002).
Stuart et al. “Replication, integration and stable germ-line transmission of foreign sequences injected into early zebrafish embryos”Development, vol. 103(2): 403-412 (1988).
Stuart et al. “Stable lines of transgenic zebrafish exhibit reproducible patterns of transgene expression”Development, vol. 109: 577-584 (1990).
Thisse & Zon “Organogenesis—heart and blood formation form the zebrafish point of view”Science, vol. 295: 457-462 (2002).
Warren et al. “The genetic basis of cardiac function: dissection by zebrafish (Danio rerio) screens”Phil. Trans. R. Soc. Lond.,vol. 355: 939-944 (2000).
Warren et al. “The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish”Am J Physiol Heart Circ Physiol, vol. 281: H1711-H1719 (2001).
Miller et al., “Imaging [Ca2+] with aequorin using a photon imaging detector,” Methods Cell Biol. 40:305-38 (1994).
Molecular Probes, “AquaLite® Recombinant Aequorin (A-6785),” MP 06785 (2001).
Office Action dated Apr. 25, 2007 in U.S. Appl. No. 10/605,415.
Bridge et al., “The relationship between charge movements associated withICaandINa-Cain cardiac myocytes,” Science, 24:376-378, (1990).
Ebert et al., “Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts,” Proc. Natl. Acad. Sci. USA, 102:17705-10 (2005).
Garrity et al., “Theheartstringsmutation in zebrafish causes heart/fin Tbx5 deficiency syndrome,” Development, 129:4635-45, (2002).
Lagenbacher et al., “Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish,” Proc. Natl. Acad. Sci. USA, 102:17699-17704 (2005).
Wakimoto et al., “Targeted disruption of Na+/Ca2+exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat,” J. Biol. Chem., 275:36991-98 (2000).
Griffith, NCBI Accession No. BX248505, (2005).
PCT Written Opinion of PCT/US/06/22295.
International Search Report of PCT/US/06/22295.

Affiliated with

Also associated with

Rating

Zebrafish assay does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Zebrafish assay, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Zebrafish assay will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4021378