Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Algae – media therefor
Patent
1991-10-15
1994-11-01
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Algae, media therefor
435 67, 4351721, 47 14, C12N 112, C12P 2300
Patent
active
053607309
ABSTRACT:
The present invention is directed toward a process for producing zeaxanthin which includes mutating algal microorganisms, selecting from said mutated microorganisms a microorganism capable of producing zeaxanthin, culturing the selected microorganism in an effective medium to produce zeaxanthin, and recovering zeaxanthin produced by the selected microorganism. The present invention also provides microorganisms capable of producing zeaxanthin, formulations containing zeaxanthin produced by the disclosed process and the use of such formulations to enhance pigmentation and to reduce damage caused by reactive oxygen species and phototoxic molecules.
REFERENCES:
patent: 2949700 (1960-04-01), Kathrein
patent: 2974044 (1961-03-01), Farrow et al.
patent: 3108402 (1963-10-01), Kathrein
patent: 3206316 (1965-09-01), Klaul
patent: 3280502 (1966-10-01), Farrow et al.
patent: 3539686 (1970-11-01), Rosenberg
patent: 3681082 (1972-08-01), Schwieter et al.
patent: 3841967 (1974-10-01), Dasek et al.
patent: 3891504 (1975-06-01), Schocher et al.
patent: 3951742 (1976-04-01), Shepherd et al.
patent: 3951743 (1976-04-01), Shepherd et al.
Moore, et al., "The Role of Carotenoids in Preventing Oxidative Damage in the Pigmented Yeast, Rhodotorula mucilaginosa", Archives of Biochemistry and Biophysics, vol. 270(2), pp. 419-431 (1989).
Krinsky, "Antioxidant Functions of Carotenoids", Free Radical Biology and Medicine, vol. 7, pp. 617-635 (1989).
Nelis and Leenheer, "Microbial Sources of Carotenoid Pigments Used in Foods and Feed", Journal of Applied Bacteriology, vol. 70, pp. 181-191 (1991).
Marusich, "Zeaxanthin as a Broiler Pigmenter", Poultry Science, vol. 55, pp. 1486-1494 (1976).
"Algae-Derived Xanthophylls for Pigmentation Control", Feeds Illustrated, vol. 13, pp. 24-25, Nov. (1962).
Spurgeon, et al., "Carotenoids", The Biochemistry of Plants, vol. 4, pp. 419-469 (1980).
Marusich, et al., "Oxycarotenoids in Poultry Pigmentation", Poultry Science, vol. 49(6), pp. 1555-1566 (1970).
Urbach, et al., "Effect of Substituted Pyridazione Herbicides and of Difunone (EMD-IT 5914) On Carotenoids in Biosynthesis in Green Algae", Naturforsch, vol. 31cZ., pp. 265-55 (1976).
Van Nostrand's Scientific Encyclopedia, pp. 79-84 (Van Nostrand Rheinhold Co. 6th Ed. 1983).
Deason, "The Genera Spongiococcum and Neospongiococcum. I. The Genus Neospongiococcum and the Multi-Nucliate Spieces of the Genus Neospongiococcum", Phycologia 10(1) pp. 17-27 (1971).
Deason, "The Genera Spongiococcum and Neospongiococcum. II. Species of Neospongiococcum with Labile Walls", Phycologia 10(2-3), pp. 255-262 (1971).
Deason, "The Genera Spongiococcum and Neospongiococcum. (Chlorophycea, Chlorococcales) III. New Species, Biochemical Characteristics and A Summary Key", Phycologia 15(2), pp. 197-213 (1976).
Deason, "Taxonomic Significance of Secondary Carotenoid Formation in Neospongiococcum", J. Phycol. 13, pp. 176-180 (1977).
Deason, "Mitosis and Cleavage During Zoosporogenesis in Several Coccoid Green Algae", J. Phycol. 15, pp. 371-378 (1979).
Parker, et al., "Facultative Heterotrophy in Some Chlorococcasean Algae" Science, vol. 133, pp. 761-763 (1961).
Khadke, et al., "The Physiology of Neospongiococcum Ovatum Deason", New Phytol., vol. 77, pp. 635-639 (1976).
Sylvester, et al., "Dark and Light Grown Algal Species of the Genus Neospongiococcum", Proceedings of the Pennsylvania Academy of Science, vol. 49(2), pp. 129-134 (1975).
Bailey and Ollis, "Kinetics of Substrate Utilization, Product Formation, and Biomass Production in Cell Cultures", Biochemical Engineering Fundamentals, ch. 7, pp. 373-456 (McGraw Hill 2d. ed. 1986).
Theriault, "Heterotrophic Growth and Production of Xanthophylls by Chorella Pyrenoidosa", Appl. Microbiol., vol. 13(3), pp. 402-416 (1965).
Bold, Morphology of Plants, p. 39 (Harper and Row, Inc., New York 1967).
Ben-Amotz, et al., Ann. Rev. Microbiol., vol. 37, p. 112 in particular, (1983).
Droop, "Algae", Methods in Microbiology, vol. 3B., ch. XI, pp. 286-299 (Academic Press, N.Y., J. R. Norris et al. eds. 1969).
Kuzmicky, et al., "Pigmentation Potency of Xanthophyll Sources" CRC Handbook of Microalgal Mass Culture, pp. 339-419 (A. Richmond ed. 1986).
Vaisberg, et al., "Events Surrounding the Early Development of Euglena Chloroplasts. 7. Inhibition of Carotenoid Biosynthesis by the Herbicide SAN 9789 [formula] and its Developmental Consequences", Plant Physiol., vol. 57(2), pp. 260-269 (1976).
Gombos et al, Plant Physiol., vol. 80(2), pp. 415-419, 1980.
Young et al, Photosynth. Res, 25(2), 129-136, 1990.
Hager et al., Archmikrobiol., 72(1), 68-83, 1970.
Brown et al, Phycologia, 21(1), pp. 9-16, 1982.
Czeczaga et al, Biochem. Syst. E col., vol. 15 (1), pp. 5-8, 1986.
Sikyta, B, "Methods in Industrial Microbiology", 1983, pp. 214-215.
Hager et al., Planta, vol. 76 (2), pp. 138-148, 1967.
Kleinig, H, Planta, vol. 75 (1), pp. 73-76, 1967.
Hunter et al., Proc. Pa Acad Sci, vol. 52 (1) 1978, p. 105.
Campbell Elizabeth A.
Medwid Richard D.
Orndorff Steve A.
Marx Irene
Universal Foods Corporation
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