Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-07-05
1997-05-27
Nazario-Gonzalez, Porfirio
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549 28, 549425, 568329, 568308, A61K 31445, C07D21130
Patent
active
056333811
ABSTRACT:
This invention relates to novel (Z,Z), (Z,E) and (E,Z) olefin isomers of substituted benzylidene cycloketones and their pharmaceutically acceptable salts. The compounds of the invention are potent factor Xa inhibitors thereby acting as anticoagulants useful in a number of thrombotic disease states. Pharmaceutical compositions are proposed for the compounds.
REFERENCES:
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Dallas Jerry L.
Guilford William J.
Koovakkat Sunil K.
Morrissey Michael M.
Shaw Kenneth J.
Bellamy Elizabeth A.
Berlex Laboratories Inc.
Hamlet-King Diana
Jones Dwayne C.
Nazario-Gonzalez Porfirio
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