Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2011-08-23
2011-08-23
Nashed, Nashaat (Department: 1656)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S193000, C435S254200, C536S023200
Reexamination Certificate
active
08003349
ABSTRACT:
The present invention relates to a novel YlMPO1 gene which plays an important role in mannosylphosphorylation of an industrial yeastYarrowia lipolytica,and to a method for preparing a host system capable of producing recombinant glycoproteins free of mannosylphosphate by disruption of the gene. The mannosylphosphorylation is suppressed by the disruption of YlMPO1 gene according to the present invention, thereby achieving humanization of glycosylation pathway ofYarrowia lipolytica.
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Kang Hyun Ah
Kim Jeong-Yoon
Oh Doo-Byoung
Park Jeong-Nam
Song Yunkyoung
Korea Research Institute of Bioscience and Biotechnology
Nashed Nashaat
Sterne Kessler Goldstein & Fox P.L.L.C.
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