Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1989-04-11
1991-02-19
Fan, Jane T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
546216, 546331, 548952, 548965, 548542, 548341, 548343, 540604, 540482, 544158, C07C31112
Patent
active
049946129
ABSTRACT:
Dihydropyridine derivatives of the formula ##STR1## wherein the symbols R and R.sup.1 to R.sup.6 have the significance given in claim 1, have a pronounced calcium-antagonist activity and can accordingly be used as medicaments, especially in the control or prevention of angina pectoris, ischemia, high blood pressure and/or migraine. The compounds of formula I can be prepared by reacting an ylidene compound of the formula ##STR2## with an enamine of the formula ##STR3##
Jaunin Roland
Ramuz Henri
Fan Jane T.
Gould George M.
Hoffmann-La Roche Inc.
Isgro William G.
Leon Bernard S.
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