Yeast promoter and use thereof

Details Yeast promoter and use thereof Yeast promoter and use thereof

2001-02-23

2009-10-20

Vogel, Nancy (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

C435S069100, C435S320100, C536S024100

Reissue Patent

active

RE040940

ABSTRACT:
The present invention concerns DNA sequences from the K. lactis PGK gene having transcriptional promoter activity. to expression vectors comprising these sequences and to their use for the production of proteins.

REFERENCES:
patent: 0361991 (1990-04-01), None
Yocum et al., Molecular and Cellular Biology, Oct. 1984, vol. 4, No. 10, p. 1985-1998.
Nucleic Acids Res. 10(8):2625-2637. 1982. Dobson, Kingsman, Tuite, Kingsman, & Roberts. Conservation of high efficiency promoter sequences in Saccharomyces cerevisiae.
Nucleic Acids Res. 18(2)365. 1990, Fournier, Fleer, Yeh, & Mayaux, The primary structure of the 3-phosphoglycerate kinase (PGK) gene from Kluyveromyces lactis.
Bio/Technology 8:135-139. 1990. van der Berg, van der Laken, van Ooyen, Renniers, Rietveld et al. Kluyveromyces as a Host for Heterologous Gene Expression: Expression and Secretion of Prochymosin.
Nucleic Acids Res. 10(23):7791-7808. 1983. Hitzeman, Hagie, Hayflick, Chen, Seeburg & Derynck The Primary Structure of the Saccharomyces cerevisiae gene for 3-phosphoglycerate kinase.
Mol. Cell Biol. 9(7):3058-3072. 1989, Linton, Yen, Selby, Chen, Chinsky et al. Dual Bidirectional Promoters at the Mouse dhfr Locus: Cloning and Characterization of two messenger RNA Classes of the divergently transcribed rep-1 gene.
EP 0361991 filed Aug. 9, 1989, issued Apr. 4, 1990. Fleer, Fukuhara & Yeh. Method for the microbiological preparation of human serum albumin and other proteins in yeast.
Dobson et al., “Conservation of High Efficency Promoter Sequences in Saccharomyces cerevisiae,” Nucleic Acids Res., vol. 10, No. 8, pp. 2625-2637 (1982).
Fournier et al., “The Primary Structure of the 3-phosphoglycerate Kinase (PGK) Gene from Kluyveromyces-lactis,” Nucleic Acids Res., vol. 18, No. 2, p. 365 (1990).
Hitzeman et al., “The Primary Structure of the Saccharomyces cerevisiae Gene for 3-Phosphoglycerate Kinase,” Nucleic Acids Res., vol. 10, No. 23, pp. 7791-7808 (1982).
Linton et al., “Dual Bidirectional Promoters at the Mouse dhfr Locus: Cloning and Characterization of Two mRNA Classes of the Divergently Transcribed Rep-1 Gene,” Mol. Cell. Biol, vol. 9, No. 7, pp. 3058-3072 (1989).
van den Berg et al., “Kluyveromyces as a Host for Heterologous Gene Expression: Expression and Secretion of Prochymosin,” Bio/Techn., vol. 8, No. 2, p. 365 (1990).

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