Yeast promoter and use thereof

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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Details

4352542, 4353201, 4351723, 530263, 536 255, 536 241, C12P 2102, C12N 119, C12N 1581, C07K 19765

Patent

active

056460120

ABSTRACT:
The present invention concerns DNA sequences from the K. lactis PGK gene having transcriptional promoter activity, to expression vectors comprising these sequences and to their use for the production of proteins.

REFERENCES:
Nucleic Acids Res. 10(8):2625-2637, 1982, Dobson, Kingsman, Tuite, Kingsman, & Roberts, Conservation of high efficiency promoter sequences in Saccharomyces cerevisiae.
Nucleic Acids Res. 18(2)365, 1990, Fournier, Fleer, Yeh, & Mayaux, The primary structure of the 3-phosphoglycerate kinase (PGK) gene from Kluyveromyces-lactis.
Bio/Technology 8:135-139, 1990, van der Berg, van der Laken, van Ooyen, Renniers, Rietveld et al. Kluyveromyces as a Host for Heterologous Gene Expression: Expression and Secretion of Prochymosin.
Nucleic Acids Res. 10(23):7791-7808, 1982, Hitzeman, Hagie, Hayflick, Chen, Seeburg & Derynck The Primary Structure of the Saccharomyces cerevisiae gene for 3-phosphoglycerate kinase.
Mol. Cell Biol. 9(7):3058-3072, 1989, Linton, Yen, Selby, Chen, Chinsky et al. Dual Bidirectional Promoters at the Mouse dhfr Locus: Cloning and Characterization of two messenger RNA Classes of the divergently transcribed rep-1 gene.
EP 0361991 filed Aug. 9, 1989, issued Apr. 4, 1990, Fleer, Fukuhara & Yeh, Method for the microbiological preparation of human serum albumin and other proteins in yeast.

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