Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2003-07-14
2009-11-03
Chen, Shin-Lin (Department: 1632)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
C435S007710, C530S350000, C514S001000
Reexamination Certificate
active
07611833
ABSTRACT:
An antiviral agent comprising an altered MAB1, MAB2, MAB3, or OLE1 gene, gene homologs or related genes is disclosed. In another embodiment, the present invention is a method of creating a virus resistant organism comprising creating a transgenic organism comprising an antiviral agent selected from the group of altered MAB1 genes, MAB2 genes, MAB3 genes or OLE1 genes, homologs of these genes, related genes and combinations of these genes and homologs.
REFERENCES:
Rudinger, 1976, Peptide Hormones, Parsons, University Park Press, Baltimore, p. 1-7.
Kaye et al., 1990, Proc. Natl. Acad. Sci. USA, vol. 87, pp. 6922-6926.
Skolnick et al., 2000, Trends in Biotech, vol. 18, p. 34-39.
P. Ahlquist, et al., “Bromovirus and Nodavirus RNA Replication,” Sixth International Symposium on Positive Strand RNA Viruses, S3-06, May 28-Jun. 2, 2001, Institut Pasteur, Paris, France (abstract).
T. Baumstark and P. Ahlquist, “The Brome Mosaic Virus RNA3 Intergenic Replication Enhancer Folds to Mimic a tRNA TYC-stem Loop and is Modified In Vivo,” Sixth international Symposium on Positive Strand RNA Viruses, P1-127, May 28-Jun. 2, 2001, Institut Pasteur, Pari, France.
T. Baumstark and P. Ahlquist, “The Brome Mosaic Virus RNA3 Intergenic Replication Enhancer Folds to Mimic a tRNA TYC-stem Loop and is Modified In Vivo,” American Society for Virology, W16-4, 20th Annual Meeting, Unversity of Wisconsin-Madison, Madison, Wisconsin, Jul. 21-25.
A.J. Caplan, at al., “Characterization of YDJ1: A Yeast Homologue of the Bacterial dnaJ Protein,” J. Cell Biol. 114(4):609-621, 1991 (front page only).
A.J. Caplan, et al., “YDJ1p Facilitates Polypeptide Translocation across Different Intracellular Membranes by a Conserved Mechanism,” Cell 71:1143-1155, 1992 (front page only).
J. Chen, et al., “Brome Mosaic Virus Replication Protein 1a Recruits Viral RNA2 to Replication through a 5′-Proximal RNA2 Replication Signal,” American Society for Virology, 19th Annual Meeting, Colorado State University, Fort Collins, Colorado, p. 129, Jul. 8-12, 2000 (abstract).
J. A. den Boon, et al., “Identification of Sequences in Brome Mosaic Virus Replicase Protein 1A that Mediate Association with Endoplasmic Reticulum Membranes,” Sixth International Symposium on Positive Strand RNA Viruses, P1-128, May 28-Jun. 2, 2001, Institut Pasteur.
J.A. den Boon, et al., “Sequences in the N-Terminal Capping Domain of Brome Mosaic Virus Replicase Protein 1A Mediate Association with Endoplasmic Reticulum Membranes,” American Society for Virology, W30-8, 20th Annual Meeting, University of Wisconsin-Madison, Madison.
J. Diez, et al., “Identification and Characterization of a Host Protein Factor Involved in Template Selection for Viral RNA Replication,” American Society for Virology, 19th Annual Meeting, Colorado State University, Fort Collins, Colorado, p. 128, Jul. 8-12, 2000 (abstract).
J. Diez, et al., “Identification and Characterization of a Host Protein Factor Involved in Template Selection for Viral RNA Replication,” PNAS 97(8):3913-3918, 2000.
H. Hermann, et al., “snRNP Sm Proteins Share Two Evolutionarily Conserved Sequence Motifs which are Involved in Sm Protein-Protein Interactions,” EMBO J. 14(9):2076-2088, 1995 (front page only).
J. Hu, et al., Hepadnavirus Assembly and Reverse Transcription Require a Multi-Component Chaperone Complex which is Incorporated into Nucleocapsids, EMBO J. 16(1):59-68, 1997.
M. Ishikawa, et al., “In Vivo DNA Expression of Functional Brome Mosaic Virus RNA Replicons inSaccharomyces cerevislae,” J. Virol. 71(10):7781-7790, 1997.
M. Ishikawa, et al., “Yeast Mutations in Multiple Complementation Groups Inhibit Brome Mosaic Virus RNA Replication and Transcription and Perturb Regulated Expression of the Viral Polymerase-Like Gene,” Proc. Natl. Acad. Sci. USA 94:7781-7790, 1997.
M. Janda and P. Ahlquist, “RNA-Dependent Replication, Transcription, and Persistence of Brome Mosaic Virus RNA Replicons inS. cerevislae,” Cell 72:961-970, 1993.
M. Janda and P. Ahlquist, “Brome Mosaic Virus RNA Replication Protein 1a Dramatically Increases In Vivo Stability but not Translation of Viral Genomic RNA3,” Proc. Natl. Acad. Sci. USA 95:2227-2232, 1998.
Y. Kimura, et al., “Role of the Protein Chaperone YDJ1 in Establishing Hsp9O-Mediated Signal Transduction Pathways,” Science 268:1362 (front page only), 1995.
D.B. Kushner and P. Ahlquist, “Turnover, Host-mediated Repair and Replication of 3′ tRNA-like Ends of Brome Mosaic Virus RNA In Vivo,” Sixth International Symposium on Positive Strand RNA Viruses, P1-127, May 28-Jun. 2, 2001, Institut Pasteur, Paris, France (abstract).
D.B. Kushner and P. Ahlquist, “Turnover, Host-mediated Repair and Replication of 3 tRNA-like Ends of Brome Mosaic Virus RNA In Vivo,” American Society for Virology, W16-10, 20th Annual Meeting, University of Wisconsin-Madison, Madison, Wisconsin, Jul. 21-25, 2001 (abstract).
D.H. Lee, et al., “Involvement of the Molecular Chaperone Ydj1 in the Ubiquitin-Dependent Degradation of Short-Lived and Abnormal Proteins inSaccharomyces cerevisiae,” Mole. Cell. Biol. 16(9):4773-4781, 1996 (front page only).
W.-M. Lee, et al., “Altered Membrane Lipid Composition Inhibits Formation of Functional Brome Mosaic Virus RNA Replication Complexes,” American Society for Virology, 19th Annual Meeting, Colorado State University, Fort Collins, Colorado, p. 129, Jul. 8-12, 2000 (abstract).
W.-M. Lee, et al., “Mutation of Host delta9 Fatty Acid Desaturase Inhibits Brome Mosaic Virus RNA Replication between Template Recognition and RNA Synthesis,” J. Virol. 75(5):2097-2106, 2001.
B.D. Lindenbach, et al., “A Long Distance Interaction in Flock House Virus RNA1 Controls Subgenomic RNA3 Synthesis,” Sixth International Symposium on Positive Strand RNA Viruses, P1-129, May 28-Jun. 2, 2001, Institut Pasteur, Paris, France (abstract).
B.D. Lindenbach, et al., “Flock House Virus Subgenomic RNA3 Synthesis is Controlled by a Long Distance Base Pairing Interaction in RNA1,” American Society for Virology, W3-2, 20th Annual Meeting, University of Wisconsin-Madison, Madison, Wisconsin, Jul. 21-25, 2001 (abstract).
A.E. McBride, et al., “Human Protein Sam68 Relocalization and Interaction with Poliovirus RNA Polymerase in Infected Cells,” Proc. Natl. Acad. Sci. USA 93:2296-2301, 1996.
D.J. Miller, et al., “Flock House Virus RNA Replicates on the Outer Mitochondrial Membrane of Drosophila Cells,” American Society for Virology, W41-4, 20th Annual Meeting, University of Wisconsin-Madison, Madison, Wisconsin, Jul. 21-25, 2001 (abstract).
E.J. Neer, at al., “The Ancient Regulatory-Protein Family of WD-Repeat Proteins,” Nature 371:297-300, 1994.
A. Noueiry and P. Ahlquist, “A Mutant Allele of DEDI, A Yeast General Translation Initiation Factor, Selectively Inhibits Translation of Bromovirus Polymerase Message,” American Society for Virology, 19th Annual Meeting, Colorado State University, Fort Collins, Colorado, p. 88, Jul. 8-12, 2000 (abstract).
A. Noueiry, et al., “A Mutant Allele of Essential, General Translation Initiation Factor DED1 Selectively Inhibits Translation of a Viral mRNA,” PNAS 97(24):12985-12990, 2000.
A. Noueiry, et al., “BMV RNA Translation Requires Host Genes Essential for Deadenylated mRNA Decapping,” Sixth International Symposium on Positive Strand RNA Viruses, S3-O6, May 28-Jun. 2, 2001, Institut Pasteur, Parison, France (abstract).
A. Neueiry, et al., “BMV RNA Translation Require Host Genes Essential for Deadenylated mRNA Decapping,” American Society for Virology, W17-3, 20th Annual Meeting, University of Wisconsin-Madison, Madison, Wisconsin, Jul. 21-25, 2001 (abstract).
R.E. O'Neill, at al., “Nuclear Import of Influenza Virus RNA can be Mediated by Viral
Ahlquist Paul G.
Diez Juana
Ishikawa Masayuki
Lee Wai-Ming
Price Duane B.
Chen Shin-Lin
Quarles & Brady LLP
Wisconsin Alumni Research Foundation
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