Yeast expression vectors for production of ITF

Details Yeast expression vectors for production of ITF Yeast expression vectors for production of ITF

2006-07-25

2009-08-18

Cochrane Carlson, Karen (Department: 1656)

Chemistry: molecular biology and microbiology

Vector, per se

C536S023100

Reexamination Certificate

active

07575920

ABSTRACT:
The invention features ITF expression vectors and methods of producing ITF.

REFERENCES:
patent: 2003/0208057 (2003-11-01), Lewin et al.
patent: 84/04330 (1984-11-01), None
patent: 2005/042010 (2005-05-01), None
Egel-Mitani et al. 1987; Nucleotide sequence of the gene encoding theSaccharomyces kluyverimating factor pheromone. Nucleic Acids Res. 15(15): 6303-6304.
Campbell et al. Mar. 2003; Embl AY264844.
Mashimo et al. 1995; Structure and expression of murine intestinal trefoil factor: High evolutionary conservation and postnatal expression. Biochem. Biophys. Res. Commun. 210(1): 31-37.
Kanai et al. 1998; Intestinal trefoil induces inactivation of extracellular signal-regulated protein kinase in intestinal epithelial cells. PNAS 95: 178-182.
PIC9 manual from Invitrogen.
Thim et al. 1993; Purification and characterization of the trefoil peptide human spasmolytic polypeptide (hSP) produced in yeast. FEBS Letters 318 (3): 345-352.
Hagenbuchle et al. 1981; Mouse liver and salivary gland a-amylase mRNAs differ only in the 5′ non-translated sequences. Nature 289:643-646.
Eurwilaichitr et al., “Glutamic Acid and Alanine Spacer is Not Necessary for Removal of MFα-1 Signal Sequence Fused to the Human Growth Hormone Produced fromPichia pastoris,” World J. Micro. Biotech. 18:493-498 (2002).
Thim et al., “Characterization of Human and Rat Intestinal Trefoil Factor Produced In Yeast,”Biochemistry34:4757-4764 (1995).
International Search Report and Written Opinion, mailed Apr. 9, 2008 (PCT/US06/28795).

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