Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2003-06-18
2009-11-03
Ulm, John D (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S254200
Reexamination Certificate
active
07611854
ABSTRACT:
Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of α-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system.
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Broach Jim
Fowlkes Dana M.
Klein Christine
Manfredi John
Murphy Andrew J.
Cadus Technologies, Inc.
Edwards Angell Palmer & & Dodge LLP
Hunter-Ensor, Esq. Melissa
Lauro, Esq. Peter C.
Ulm John D
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