Yeast cell expressing heterologous receptor kinase

Details Yeast cell expressing heterologous receptor kinase Yeast cell expressing heterologous receptor kinase

1994-07-22

1996-11-12

Ulm, John

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 691, 4353201, 536 235, C12N 119, C12N 1581

Patent

active

055739440

ABSTRACT:
Disclosed herein are compositions and methods which are useful in the identification and isolation of components involved in transmembrane receptor-mediated signaling. Such components include the receptors themselves (e.g., tyrosine kinase receptors, cytokine receptors and tyrosine phosphatase receptors), as well as ligands which bind the receptors and modulators of the downstream intracellular catalytic event which characterizes receptor-mediated signalling.

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Holmes et al., Science 253:1278-1280, 13 Sep. 1991.
Florio et al., Molecular Biology of the Cell, vol. 5: 283 (1994).
Keating and Williams, Science, vol. 239: 914 (1988).

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