YAK-1 related serine/threonine protein kinase-HTLAR33

Details YAK-1 related serine/threonine protein kinase-HTLAR33 YAK-1 related serine/threonine protein kinase-HTLAR33

1998-02-20

2000-10-17

Lau, Kawai

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435455, 435468, 435471, 4352523, 43525411, 4353201, 536 232, C12N 912, C12N 121, C12N 1563, C07H 2104

Patent

active

06133006&

ABSTRACT:
HTLAR33 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HTLAR33 polypeptides and polynucleotides in therapy, and diagnostic assays for such.

REFERENCES:
Kentrup, H. et al., "Dyrk, a Dual Specificity Protein Kinase with Unique Structural Features . . . ", J. Biol. Chem 271(7):3488-3495 (1996).
Tejedor, F. et al., "minibrain: A New Protein Kinase Family Involved in Postembryonic Neurogenesis in Drosophila", Neuron (14):287-301 (1995).
Garrett et al. "The Saccharomyces cerevisiae YAK1 Gene Encodes a Protein Kinase that Is Induced by Arrest Early in the Cell Cycle", Molecular and Cellular Biology, vol. 11(8), pp. 4045-4052 (1991).
Tugendreich et al. "Linking yeast genetics to mammalian genomes: Identification and mapping of the human Homolog of CDC27 via the expressed sequence tag (EST) data base", Proc. Natl. Acad. Sci. USA, vol. (90), pp. 10031-10035 (1993).
Song et al. Isolation of Human and Murine Homologues of the Drosophila Minibrain Gene: Human Homologue Maps to 21q22.2 in the Down Syndrome "Critical Region", Genomics, vol. 38, pp. 331-339 (1996).
Copy of Partial EP Search Report.

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