Y2H56 A strong IKK binding protein

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

536 235, 536 231, 530350, 4352523, 4353201, C12P 2106, C12N 120, C07H 2104, C07H 2102, C07H 100

Patent

active

060664746

ABSTRACT:
The present invention provides an isolated I.kappa.B kinase binding protein designated Y2H56 and functional equivalents therof. The amino acid sequence of Y2H56, the nucleotide sequence encoding Y2H56, and other related protein and nucleic acid molecules are also provided.

REFERENCES:
patent: 5776717 (1998-07-01), Cao
patent: 5804374 (1998-09-01), Baltimore et al.
Mock et al., "CHUK, a Conserved Helix-Loop-Helix Ubiquitous Kinase, Maps to Human Chromosome 10 and Mouse Chromosome 19", Genomics 27:348-351 (1995).
Margery A. Connelly and Kenneth B. Marcu, "CHUK, a New Member of the Helix-Loop-Helix and Leucine Zipper Families of Interacting Proteins, Contains a Serine-Threonine Kinase Catalytic Domain", Cellular and Molecular Biology Research 41:537-549 (1995).
Garkavtsev, et al., "Suppression of the novel growth inhibitor p33.sup.ING1 promotes neoplastic transformation", Nature Genetics 14:415-420 (1996).
DiDonato et al., "A Cytokine-Responsive I.kappa.B Kinase That Activates the Transcription Factor NF-.kappa.B", Nature 388:548-554 (1997).
Regnier et al., "Identification and Characterization of an I.kappa.B Kinase", Cell 90:373-383 (1997).
Ilana Stancovski and David Baltimore, "NF-.kappa.B Activation: The I.kappa.B Kinase Revealed?", Cell 91:299-302 (1997).
Woronicz et al., "I.kappa.B Kinase-.beta.: NF-.kappa.B Activation and Complex Formation with I.kappa.B Kinase-.alpha. and NIK", Science 278:866-869 (1997).
Zandi et al., "The I.kappa.B Kinase Complex (IKK) Contains Two Kinase Subunits, IKK.alpha. and IKK.beta., Necessary for I.kappa.B Phosphorylation and NF-.kappa.B Activation", Cell 91:243-252 (1997).
Garkavtsev, et al., "The candidate tumour suppressor p33.sup.ING1 cooperates with p53 in cell growth control", Nature 391:295-298 (1998).
Moshe Oren, "Teaming up to restrain cancer", Nature 391:233-234 (1998).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Y2H56 A strong IKK binding protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Y2H56 A strong IKK binding protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Y2H56 A strong IKK binding protein will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1836038

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.