Y-chromosome specific polynucleotide probes for prenatal sexing

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, 536 243, C12Q 168, C12P 1934, C07H 2104

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active

056630484

ABSTRACT:
Y-chromosome specific hybridization probes for prenatal sexing are provided capable of hybridizing only to Y-chromosome specific DNA sequences of bovine and other ruminants and are suitable for sexing embryos at or before the time of embryo transfer with essentially 100% accuracy.

REFERENCES:
patent: 4769319 (1988-09-01), Ellis et al.
patent: 4960690 (1990-10-01), Ellis et al.
patent: 5215884 (1993-06-01), McGraw, III
Page et al., (1987) "The sex-determining region of the human Y chromosome encodes a finger protein" Cell 51: 1091-1104.
Mardon & Page (1989) "The sex-determining region of the mouse Y chromosome encodes a protein with a highly acidic domain and 13 zinc fingers" Cell 56: 765-770.
Koopman et al. (1989) "Zfy gene expression patterns are not compatible with a primary role in mouse sex determination" Nature 342:940-942.
Palmer et al. (1989) "Genetic Evidence that ZFY is not the testis-determining factor" Nature 342:937-939.
Burgoyne (1989) "Thumbs down for zinc finger?" Nature 342:860-862.
Leonard et al. (1987) "Sexing bovine embryos using Y Chromosome specific DNA probe" Theriogenology 27:248 (abstract).
Bondioli et al. (1989) "The use of male-specific chromosomal DNA fragments to determine the sex of bovine preimplantation embryos" Theriogenology 31:95-104.
Vaiman et al., (1988) "Sexing of bovine embryos using male-specific nucleic acid probes" Third World Congress Sheep and Beef Cattle Breeding. 93-105.
Matthews et al, Analyti. Biochem 169:1-25 (1988).
Maniatis et al, "Molecular Cloning" (1982) p. 388.
Nakahori et al., Am J. Med. Genetic 39: 472-973 (1991) "Sex Identification by PCR . . . ".

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