Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification
Reexamination Certificate
2007-09-27
2010-06-22
Vogel, Nancy (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
C435S252100
Reexamination Certificate
active
07741119
ABSTRACT:
A strain of xylose-utilizingZymomonaswas engineered with a genetic modification to the glucose-fructose oxidoreductase gene resulting in reduced expression of GFOR enzyme activity. The engineered strain exhibits reduced production of xylitol, a detrimental by-product of xylose metabolism. It also consumes more xylose and produces more ethanol during mixed sugar fermentation under process-relevant conditions.
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Chou Yat-Chen
McCutchen Carol M.
Viitanen Paul V.
Zhang Min
Alliance for Sustainable Energy LLC
E. I. du Pont de Nemours and Company
Vogel Nancy
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