Xylitol dehydrogenase of acetic acid bacteria and gene thereof

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

Reexamination Certificate

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C435S320100, C435S252300, C435S006120, C536S023200

Reexamination Certificate

active

06924131

ABSTRACT:
Xylitol is produced by allowing xylitol dehydrogenase or cells instoduced with a DNA coding for xylitol dehydrogenase, which is a protein of the following (A) or (B) to act on D-xylulose, and collecting produced xylitol:(A) a protein which has the amino acid sequence of SEQ ID NO: 4;(B) a protein which has the amino acid sequence of SEQ ID NO: 4 including substitution, deletion, insertion, addition, or inversion of one or several amino acids, and has xylitol dehydrogenase activity.

REFERENCES:
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patent: 6303353 (2001-10-01), Sugiyama et al.
patent: 6340582 (2002-01-01), Suzuki et al.
patent: WO 94/10325 (1994-05-01), None
patent: WO 99/20782 (1999-04-01), None
Yoshida et al., Microbiology, 142, 3113-3123, 1996.
Derwent Publications, AN 1972-27535, JP 47 013707, Apr. 25, 1972, Abstract.
B. Persson, et al., FEBS Letters, Dual Relationships of Xylitol and Alcohol Dehydrogenases in Families of Two Protein Types, Jun. 1993, vol. 324, No. 1, pp. 9-14.
M. A. Gallo, et al., EMBL Database Entry Mmxylitol, Accession No. L34345, 5 pages, “Molecular Characterization of Xylitol Catabolic Pathways in the Enterobacteriaceae”, Aug. 4, 1994.

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