Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-08-23
1998-10-27
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514414, 548453, A61K 3140, C07D49502
Patent
active
058278729
ABSTRACT:
The invention is drawn to novel antibiotics, xenomins of the formula shown below, ##STR1## wherein R.sub.1 =hydrogen; R.sub.2 =an unsubstituted acyl group; R.sub.3 =hydrogen or alkyl, produced by Xenorhabdus species, the salts thereof, the compositions thereof and their use as medicaments and/or agrochemicals, particularly in the treatment of infectious diseases involving microorganisms susceptible to them, including drug-resistant Staphylococcus, and in the treatment of human and animal cancers.
REFERENCES:
patent: 8412455 (1995-03-01), Webster et al.
patent: 8420307 (1995-03-01), Webster et al.
patent: 8627589 (1996-08-01), Webster et al.
Akhurst, R. J. and N. E. Boemare, 1988. .J. Gen. Microbiol. vol. 134, 1835-1845.
Forst, S. and K. Nealson, 1996. Microbiol. Rev. 60:21-43.
Bergeron et al. 1984. Biochem. Bioph. Res. Comm. 121:845-854.
Chen, G et al., 1994. Biological Control 4:157-162.
Li, J. et al., 1995. J. Nat. Prod. 58:1081-1085.
Li, J. et al., 1995. Appl. Environ. Microbiol. 61:4329-4333.
Skehan, P. et al., 1990. J. Natl. Cancer Inst 82:1107-1118.
The National Committee for Clinical Laboratory Standards, 1990. Pa.
Chen Genhui
Li Jianxiong
Webster John M.
Coleman Brenda
Raymond Richard L.
LandOfFree
Xenomins novel heterocyclic compounds with antimicrobial and ant does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Xenomins novel heterocyclic compounds with antimicrobial and ant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Xenomins novel heterocyclic compounds with antimicrobial and ant will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1614176