Xenobiotic delivery vehicles, method of forming them and method

Details Xenobiotic delivery vehicles, method of forming them and method Xenobiotic delivery vehicles, method of forming them and method

1980-04-04

1981-11-03

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 38, A61K 922, A61K 942, A61K 952

Patent

active

042985943

ABSTRACT:
A vehicle suitable for delivering a xenobiotic to a mammalian host to beneficially alter the pharmacodynamics (e.g., plasma kinetics, chemotherapeutic effectiveness, toxicity, oral absorption, tissue distribution, metabolism and the like) of the xenobiotic. The delivery vehicle is in the form of microreservoirs formed of a phospholipid constituent and a phospholipid-immiscible constituent. Xenobiotic binding agents and release agents may be added. Methods for preparing the microreservoirs containing the xenobiotic and for administering a xenobiotic to beneficially alter its pharmacodynamics are disclosed.

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