Xanthine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544267, 544273, 544272, A61K 3152, C07D47300

Patent

active

050682369

ABSTRACT:
Novel xanthine compounds represented by the following formula: ##STR1## and pharmaceutically acceptable salts thereof have a diuretic action, a renal-protecting action and a vasodilative action.
The compounds are useful as a diuretic, a renal-protecting agent and an antihypertensive agent.

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Chemical Abstract vol. 58 (1963) 10218b of von Schuh et al. German Patent 1,140,581.
The Merck Index, 10th ed., 9114 (1983).
J. Am. Chem. Soc., vol. 75, 114 (1953).
J. Med. Chem., vol. 14, No. 12, 1202 (1971).
Brit. J. Pharm., vol. 97, 502P (1989).
Brit. J. Pharm., vol. 96, 31P (1989).

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