Xanthine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544267, 544272, 544273, A61K 3152, C07D47302

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active

053428412

ABSTRACT:
A xanthine derivative of the formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are substituted or unsubstituted alicyclic alkyl; m1 and m2 are the same or different and represent an integer of 0 to 2; and Q represents ##STR2## (in which R.sup.3 and R.sup.4 are the same or different and are substituted or unsubstituted alicyclic alkyl) or ##STR3## (in which n is 0 or 1, and Y is a single bond or alkylene); or a pharmaceutically acceptable salt thereof is disclosed.
This derivative has diuretic activity and renal protecting activity.

REFERENCES:
patent: 4233303 (1980-11-01), Bergstrand et al.
patent: 4713455 (1987-12-01), Furrer et al.
patent: 5068236 (1991-11-01), Suzuki et al.
Chemical Abstracts, vol. 108, No. 11 (1988) 945125.
Chemical Abstracts, vol. 109, No. 25 (1988) 221931a.
Chemical Abstracts, vol. 106, No. 19 (1987) 149315w.
Chemical Abstracts, vol. 113, No. 9 (1990) 78009f.

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