Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-03-10
1994-08-30
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544267, 544272, 544273, A61K 3152, C07D47302
Patent
active
053428412
ABSTRACT:
A xanthine derivative of the formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are substituted or unsubstituted alicyclic alkyl; m1 and m2 are the same or different and represent an integer of 0 to 2; and Q represents ##STR2## (in which R.sup.3 and R.sup.4 are the same or different and are substituted or unsubstituted alicyclic alkyl) or ##STR3## (in which n is 0 or 1, and Y is a single bond or alkylene); or a pharmaceutically acceptable salt thereof is disclosed.
This derivative has diuretic activity and renal protecting activity.
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patent: 5068236 (1991-11-01), Suzuki et al.
Chemical Abstracts, vol. 108, No. 11 (1988) 945125.
Chemical Abstracts, vol. 109, No. 25 (1988) 221931a.
Chemical Abstracts, vol. 106, No. 19 (1987) 149315w.
Chemical Abstracts, vol. 113, No. 9 (1990) 78009f.
Karasawa Akira
Kase Hiroshi
Mizumoto Hideaki
Nonaka Hiromi
Shimada Jun'ichi
Ford John M.
Kyowa Hakko Kogyo Co. Ltd.
Sripada Payanaram K.
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