Xanthene dyes that emit to the red of fluorescein

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435724, 435 75, 435 19, 435 29, 435960, 435968, 436800, 436805, 436 63, 424 3, C12Q 100, C12Q 144, C12Q 102, G01N 3353, G01N 3348, G01N 130, G01N 3100

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050665804

ABSTRACT:
Novel xanthene dyes are disclosed which excite in the range of 450-650 nm and which will emit to the red of fluoroscein. These dyes may be coupled to tagging agents, such as monoclonal antibodies, and used to detect cells in a sample.

REFERENCES:
patent: 4599307 (1986-07-01), Saunders et al.
patent: 4727020 (1988-02-01), Recktenwald
Orndorff et al., J. Am. Chem. Soc., 46:1986, 1924.
Herzenberg et al., Sci. Am., 234:10, 1976.
Rink et al., J. Cell. Biol., 95-189, 1982.

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